| 학회 |
한국화학공학회 |
| 학술대회 |
2018년 가을 (10/24 ~ 10/26, 대구 EXCO) |
| 권호 |
24권 2호, p.1501 |
| 발표분야 |
생물화공(Biochemical Engineering) |
| 제목 |
Optimization of polymerization conditions for enhanced in-vitro hemozoin production by enzymatic process |
| 초록 |
Recently, conductive polymers have receiving attention in industrial nano-biotechnology due to its tremendous potential for a variety of applications such as electronics, robots, energy devices, bio-chips and composites as a viable alternative to semi-conductive materials or energy sources. In this study, to determine the potential applicability of hemozoin, the conductivity of heme (monomer of hemozoin) was mesaured as 4.0 × 10-3 μS/cm. The polymerization of hemozoin by using HRP-Ⅱ was performed in vitro system and the qualitative analysis of produced hemozoin was confirmed by FT-IR, EDS and SEM. To improve the in vitro production of hemozoin, the effect of reaction factors on the polymerization was investigated. The maximum production of hemozoin was achieved about 790 μM at 34°C, 200 rpm in shaking incubator for 24 h, and the production was 2-fold improved according to the stepwise optimization in vitro system. |
| 저자 |
이주훈1, 이수권1, 김형렬1, 이희욱1, 유하영2, 김승욱1
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| 소속 |
1고려대, 2상명대 |
| 키워드 |
생물화공 |
| E-Mail |
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| 원문파일 |
초록 보기 |
