초록 |
Fluorescence labeling is a very important analytical technique for probing the structure of living cells. Inorganic quantum dots have been used in the field due to their high quantum yield, high molar extinction coefficients, broad absorption with narrow light emission, and good photo physical and chemical stability. Despite of these promising properties of semi-conducting quantum dots for fluorescence labeling, cyto-toxicity is a critical problem in any living cell or animal experiments. Alternative choices are dye-loaded latex particles and dye-doped silica colloids having improved photostability compared to conventional dye molecules. However, dye-loaded particles also have a critical limit of brightness due to the self-quenching when high density of dyes present at the nanoparticle surface. Thus, developing highly emissive, biocompatible, and chemically modifiable luminescent materials is strongly desired.Here, we report the enhanced photoluminescence of a quinoline derivative for possible use in the field of immunofluorescence labeling. |