| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
고분자가공/복합재료 |
| 제목 |
Highly sensitive metal-enhanced fluorescence biosensor prepared on electrospun PCL fibers decorated with silica-coated silver nanoparticles |
| 초록 |
A new MEF-based biosensor platform was prepared on fibrous substrates. First, PCL fibers were obtained via electrospinning. PCL fibers were decorated with photoreduced silver nanoparticles followed by silica coating, generating silver-decorated PCL fibers with a silica layer. The silica layer acted as a spacer between the silver nanoparticles and the fluorescent molecules to optimize the MEF effect. The MEF was obtained from the silver-decorated PCL fibers, the extent of which could be controlled by the thickness of the silica layer. The fibrous structure of Ag@SiO2-PCL had higher protein loading capacity than conventional two-dimensional glass slides due to its large surface area, while the presence of silica-coated silver nanoparticles resulted in higher fluorescence intensity than SiO2-PCL without silver nanoparticles via the MEF effect. |
| 저자 |
윤병주, 조강희, 홍혜진, 강성민, 최주환, 김혜원, 고원건
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| 소속 |
연세대 |
| 키워드 |
Metal-enhanced fluorescence; Fibrous substrates; Silver-decorated fibers; Silica layer; Fluorescence-based immunoassay
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| E-Mail |
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