학회 | 한국재료학회 |
학술대회 | 2019년 가을 (10/30 ~ 11/01, 삼척 쏠비치 호텔&리조트) |
권호 | 25권 2호 |
발표분야 | 특별심포지엄9. 여성위원회 특별세션-오거나이저:윤희숙(KIMS) |
제목 | 이차원 나노그래핀 융합형 조직재생공학 소재 |
초록 | Tissue regenerative materials require many features such as biocompatibility, biodegradability, bio-stability, and rigidity depending on target tissue. Guided tissue regeneration (GTR) membranes have been used to maintain adequate space and prevent ingrowth of soft tissue during bone healing period. Thus, mechanical properties and biological properties are very important for GTR membranes. In order to enhance the mechanical properties of GTR membrane, particularly rigidity, numerous physical and chemical modifications including structure alignment, crosslinking, and compositing with other materials have been carried out. Among them, incorporating additives is one of the simple and effective methods to strengthen GTR membrane. The additive materials for bioengineering are generally strong, biocompatible or bioactive, and functional for the delivery of therapeutic molecules. Graphene is receiving growing attention as a prospective material in biomedical research fields due to its fascinating properties such as high surface area, excellent mechanical strength, extraordinary elasticity, and great electronic conductivity. Recent studies have reported that graphene has potential of improving mechanical properties and osteogenic responses for hard tissue engineering. Moreover, graphene can interact with other materials including biopolymers and therapeutic molecules through covalent and non-covalent bonding. As an additive material, graphene, has advantages of producing nanocomposites with strong interface between polymeric matrix with drug delivery ability. In this presentation we propose an effective method to fabricate graphene-incorporated composites with uniform microstructure. The developed method is suitable to produce bioengineered graphene-based composites with tunable mechanical and physical properties as well as good biocompatibility, thus providing cell-favorable microenvironment for tissue engineering. |
저자 | 이은정 |
소속 | 단국대 |
키워드 | 그래핀; 조직공학; 융합; 조직재생 |