| 학회 |
한국공업화학회 |
| 학술대회 |
2006년 가을 (11/10 ~ 11/11, 경희대학교(수원캠퍼스)) |
| 권호 |
10권 2호 |
| 발표분야 |
우수논문 |
| 제목 |
Design, solid phase synthesis and screening of N-(3- hydroxysulfonyl)-L-homoserine lactone analogues as new quorum sensing antagonists |
| 초록 |
A series of 8 new analogues of N-(3- hydroxysulfonyl)-L-homoserine lactone(HSL) has been synthesized by solid-phase organic synthesis method. Each of 8 synthesized compounds was given such tests as NMR, mass spectroscopy. Then followed a bacterial test designed to identify quorum-sensing inhibition activity and antifouling efficacy of those compounds. 8 synthesized compounds were found to be effective as quorum-sensing inhibitors. |
| 저자 |
김철진, 윤제용, 김재은, 연경민, 이정학
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| 소속 |
서울대 |
| 키워드 |
quorum-sensing antagonist of bacteria; autoinducer; N-acylhomoserine lactone
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| E-Mail |
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