| 초록 |
For developing new and expedient methods as a substitute for immunosensor, some attention has been focused on aptamer-based methods to detect biological markers. Since the aptamer has a high binding affinity and selectivity for its target molecules such as antibodies, it is suitable as a powerful biological diagnostic tool. Also, aptamers have several advantages over antibodies, such as chemical synthesis in vitro, easy modification, and low cost. Moreover, aptamers are resistant in various buffer conditions, pH, and temperature. In this presentation, current approaches for the development of electrochemical bio-sensors using various aptamers will be discussed based on the following subtopics; (1) Detection of both PSMA(+) and PSMA(-) prostate cancer cells using an RNA/peptide dual-aptamer probe (5) Development of biosensor for detection of sulfadimethoxine |
