| 학회 |
한국공업화학회 |
| 학술대회 |
2011년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터) |
| 권호 |
15권 1호 |
| 발표분야 |
우수논문발표(구두) |
| 제목 |
Large-Scale Synthesis of Bioinert Tantalum Oxide Nanoparticles for X-ray Computed Tomography Imaging and Bimodal Image-Guided Sentinel Lymph Node Mapping |
| 초록 |
Ever since Au nanoparticles were developed as X-ray contrast agents, researchers havesought alternative nanoparticle-based imaging probes that are not only inexpensive but also safe for clinical use. Herein we demonstrate that bioinert tantalum oxide nanoparticles are suitable nanoprobes for high-performance X-ray CT imaging while simultaneously being cost-effective and meeting the criteria as a biomedical platform. Uniformly sized tantalum oxide nanoparticles exhibited remarkable performances in in vivo X-ray CT angiography and bimodal image-guided lymph node mapping. We also performed an extensive study on in vivo toxicity of tantalum oxide nanoparticles, revealing that the nanoparticles did not affect normal functioning of organs. |
| 저자 |
오명환, 현택환
|
| 소속 |
서울대 |
| 키워드 |
Tantalum oxide; nanoparticle; X-ray contrast agent; angiography; lymph node mapping
|
| E-Mail |
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