초록 |
Tissue adhesives are increasingly important elements in modern medicine, with rapid development over the past 30 years. They provide versatile materials for wound management and are widely used in a variety of medical settings ranging from minor to life-threatening tissue injuries. However, most of the conventionally used adhesives for the body are toxic or have a risk of viral infection. Therefore, the development of novel adhesives requires a systematic understanding of the chemical and physical properties of the tissue-adhesive interface, the underlying mechanisms of tissue adhesion. We prepared a biocompatible adhesive using natural polymers. Adhesive and mechanical behavior were controlled by various types of solvent. The effect of the solvent on the crystal structure was also studied. This material exhibited a specific adhesion behavior dependent on the bio tissue site. Accordingly, we examined the correlation between the compositions of each tissue and the adhesive strength. |