| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 가을 (10/06 ~ 10/08, 제주 ICC) |
| 권호 |
39권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Fabrication of chitosan-g-poly(methyl vinyl ketone) nanoporous microspheres by photodegradation for controlled drug delivery system |
| 초록 |
Chitosan(CS) is a well-known natural polysaccharide with good biocompatibility and biodegradability. Graft copolymerization of poly(methyl vinyl ketone)[PMVK] onto chitosan was conducted by free radical method using KPS or CAN as an initiator. Nanoporous microspheres were synthesized by water-in-oil(W/O) emulsion method with glutaraldehyde(GA), Tween80® as crosslinking agent and emulsifier, followed by UV irradiation to confer nanopores by photodegradation of PMVK. Graft copolymer was characterized by FT-IR and thermal methods. SEM showed CS-g-PMVK microspheres were approximately 5 ㎛ in diameter with nanosized pores due to photodegradation of PMVK by UV irradiation. |
| 저자 |
김지선, 김태윤, 정일두
|
| 소속 |
부산대 |
| 키워드 |
photodegradation; microsphere; chitosan; nanoporous; controlled drug delivery system
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| E-Mail |
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