화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2011년 봄 (04/07 ~ 04/08, 대전컨벤션센터)
권호 36권 1호
발표분야 고분자 합성
제목 Nanoparticles for Drug Delivery Prepared from Copolypeptide
초록 The stability and targeting efficiency of nanoparticles (NPs) are the two most important factors for their successful application to drug delivery and diagnostic imaging. Herein we describe the synthesis of copolypeptide containing 3,4-dihydroxy -phenyl amino acid (DOPA) and Aspartic acid by ring-opening polymerization of new uracil and -amino acid N-carboxyanhydride (NCA) monomers respectively. It is further demonstrated that the copolypeptide can Self-assembled into NPs with drug delivery capability.
저자 황신화, 하창식, 김일
소속 부산대
키워드 copolypeptide; drug delivery; nanoparticles (NPs); ring-opening; self-assembled
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