| 학회 | 한국공업화학회 |
| 학술대회 | 2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 | 23권 2호 |
| 발표분야 | 포스터_생체재료 |
| 제목 | Anti-calcification properties of zwitterionic polymer grafted polyurethane surfaces |
| 초록 | Calcification of implantable devices has been a major issue. To overcome this, surface modification with anti-fouling ability has been used, and zwitterionic materials have already been reported to have great anti-fouling ability. In this study, the surface modification was developed for anti-calcification property by grafting zwitterionic polymers (poly(sulfobetaine methacrylate-co-tyramine) (pSBTA)) onto polyurethane surfaces via facile enzyme-mediated reaction. The in vivo anti-calcification effects were analyzed by ICP (reduced Ca ion amounts (75.6 to 45.6 μg/cm2)). These results suggest that surfaces modified with pSBTA could be promising candidates for implantable medical devices with anti-calcification. Acknowledgement: NRF-2015M3A9E2028578, MOTIE/KEIT [10062079] |
| 저자 | 김흥주1, 박경민2, 박기동1 |
| 소속 | 1아주대, 2인천대 |
| 키워드 | Surface modification; zwitterionic material; anti-calcification |
