| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 봄 (04/07 ~ 04/08, 대전컨벤션센터) |
| 권호 |
36권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Polymer-Coated Tips for Patterning of Viruses by Dip-Pen Nanolithography |
| 초록 |
Dip-pen nanolithography(DPN) allows one to directly print a wide variety of biomolecules in a surface with high resolution. This technique has potential applications for gene chips and multiple biomolecular arrys because one can create patterns with numerous molecules in a direct-write fashion. In this work, we generated adeno-associated viruses(AAVs) nanostructures by nano porous poly(2-methyl-2-oxazoline)(PMeOx) coated tip. This tip was fabricated by ring opening polymerization of 2-methyl-2-oxazoline monomers on the tip surface. In conclusion, we have developed a straightforward and effective DPN method that uses a nanoporous PMeOx-coated tip to generate patterns of large sized viruses. The nano-porous polymer coated tip and pattern of viruses were characterized with AFM, SEM and fluorescent microscope. |
| 저자 |
김기훈, 신용훈, 남지혜, 김지은, 김경민, 임정혁
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| 소속 |
충주대 |
| 키워드 |
: dip-pen nanolithography; AAV particle; Nano porous polymer coated tip; ring opening polymerization
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| E-Mail |
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