| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
37권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Synthesis and characterization of novel block copolymer ; Poly(lactic acid-b-γ-amino butyric acid) |
| 초록 |
Novel block copolymer of Poly(lactic acid-b-γ-amino butyric acid(GABA)) were synthesized for a controlled drug delivery and a release of GABA. The block copolymer was prepared by ring openig polymerization of 2-pyrrolidone in activated end group of poly(lactic acid) which was substituted with dehydrated 2-pyrrolidone. The block copolymer was confirmed by FT-IR and 1H NMR spectroscopy. Sol-gel transition and biodegradation of the block coplymer were investigated for using as drug carrier. Release behavior of GABA derivatives using in control of neurological pain was analyzed. |
| 저자 |
김자원, 김홍성, 임소령, 정수진, 김준
|
| 소속 |
부산대 |
| 키워드 |
GABA; PLA; biodegradation; block copolymer
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| E-Mail |
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