| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
38권 2호 |
| 발표분야 |
기능성 고분자 (포스터발표만 진행) |
| 제목 |
Preparation and characterization of poly(acrylic acid)/poly(ethylene glycol) hydrogel for buccal mucosa adhesion by radiation |
| 초록 |
The aim of the present study is to develop a suitable poly(acrylic acid)(PAA)-based mucoadhesive which might have potential for the localized prolonged delivery of active agents into an oral cavity. In this experiment, PAA and poly(ethylene glycol)(PEG) were selected for preparing the bioadhesive hydrogel adhering to mucosal surfaces using a radiation process. PAA was dissolved in purified water, and PEG was then incorporated into the PAA solution. Finally, the mixture was irradiated by electron beam accelerator to make hydrogel. Their physical properties such as gel percent, swelling percent, compressive strength, and adhesive strength to mucosal surfaces have been investigated. |
| 저자 |
박종석1, 신정웅1, 최종배1, 정진오1, 임종영1, 임윤묵1, 권희정1, 정성린1, 신영민1, 임돈순1, 신상훈2, 강필현1, 노영창1
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| 소속 |
1한국원자력(연), 2충남대 |
| 키워드 |
Mucoadhesion; Polyacrylic acid (PAA); Hydrogel; Electron beam;
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| E-Mail |
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