| 초록 |
In this study, we investigated the antibacterial properties of low molecular weight water-soluble chitosanusing a combination of approaches, including MIC estimations at 2 different pH values, bactericidal kinetics, calcein-loaded liposomes, depolarization assay, and electron microscopy, as well as an in vivo study utilizing a wound infection and wound healing model. The antibacterial activity of LMWSC was inversely related to pH, with higher activities being observed at lower pH values. This study was supported by IPET(Korea Institute of planning & Evaluation for Technology in Food, Agriculture, Forestry & Fisheries) Research Fund in 2009. |
