초록 |
This paper introduces a facile method to make a highly stable and recyclable antimicrobial magnetic nanoparticle. This nanoparticle was prepared by the deposition of silver nanoparticles (AgNPs) onto the catechol derivatives 2-chloro-3', 4’-dihydroxyacetophenone conjugated with poly (vinyl pyrrolidone) coated magnetic iron oxide nanoparticles (IONPs). This nanoparticles showed long term colloidal stability and redispersibility, respectively, against an external magnet and a broad range of pH. The magnetic nanoparticle was characterized by UV-vis, TEM, SEM, XPS, and DLS measurement. The nanoparticles possessed a high antibacterial activity against the model microbes and could be separated easily using magnet for repeated uses and maintained 100% antibacterial efficiency during first three cycles. The synthesized magnetic nanoparticles showed no measureable cytotoxicity to live cells in MTT assay. |