화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 봄 (04/09 ~ 04/10, 대전컨벤션센터)
권호 34권 1호
발표분야 Polymer micro/nano bio-fabrication(의료용 고분자 부문위원회)
제목 "Small" Tools for Neuroscience and Stem Cell Research
초록 This presentation will describe the development and application of novel microfluidic devices for neuroscience and stem cell research. Microfluidic systems offer several advantages over traditional cell culture models due to its ability to control precise microenvironment in space and time when applied to cell biology problems. This presentation will describe (1) gradient-generating microfluidic devices that are used to understand axon guidance, cell migration and stem-cell differentiation/differentiation and (2) a microfluidic neuronal culture platform that combines microfabrication and surface micropatterning approaches to create an experimental platform for neuroscience research. The ability to direct sites of neuronal attachment and orientation of axon outgrowth by micropatterning techniques, combined with fluidically isolated compartments within the culture area offer significant advantages over conventional methods for manipulating distinct cellular microenvironments.
저자 전누리
소속 서울대
키워드 microfluidics; neuron; stem cell
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