| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
생물공학_포스터 |
| 제목 |
Changes of biological activity of Rhodiola sachalinesis according to extraction conditions |
| 초록 |
HKC possess a wide range of pharmacological activities. The changes of biological activity were investigated by using various solvents and extraction methods. The recovery rate was significantly higer when using the ultrasonic extraction method than when using water and ethanol. In addition, radical scavcenging activity of DPPH and ABTS was also significantly higher when extracted with ultrasonic than water and ethanol extraction. Based on these results, we investigated the inhibitory effect of ROS on the induction of intracellular oxidative stress. The ROS produced by oxidative stress induced by H2O2 in the HaCaT cells was significantly decreased in a concentration-dependent manner by the ultrasonic extract. In other words, the HKC extract through ultrasonic extraction significantly improved the antioxidative activity as well as ROS production by oxidative stress. Therefore, it is confirmed that the activity of natural materials is changed according to the extraction method. |
| 저자 |
안소희1, 박현지1, 김민주1, 김예진1, 김은지1, 권미진2, 이계원1, 조영호1
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| 소속 |
1건양대, 2(주)PSA |
| 키워드 |
Rhodiola sachalinesis; antioxidant activity; ultrasonic extraction; Cosmetic materials; oxidative stress
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| E-Mail |
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