학회 | 한국공업화학회 |
학술대회 | 2007년 가을 (11/02 ~ 11/03, 한경대학교) |
권호 | 11권 2호 |
발표분야 | 정밀화학 |
제목 | Stereodivergent approach to syn and anti isomers of γ-amino-β-hydroxy acids: (3S,4S)- and (3R,4S)-AHPPA derivatives |
초록 | A stereodivergent approach, controlled by N-hydroxymethyl group via intramolecular conjugate addition and intramolecular epoxidation reaction, has been developed to obtain (3S,4S)-AHPPA and (3R,4S)-AHPPA derivatives stereoselectively. Selectivity of the intramolecular conjugate addition was more than 10 to 1 and that of intramolecular epoxidation was more than 20 to 1. |
저자 | 강은실, 김영규, 송지윤, 유동원, 강문성 |
소속 | 서울대 |
키워드 | AHPPA; N-hydroxymethyl group; intramolecular conjugate addition; intramolecular epoxidation |