| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO)) |
| 권호 |
40권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Tracheal Tissue Regeneration within Asymmetrically Porous Tube Combined with 3D Printed Scaffold |
| 초록 |
Reconstruction of the damaged trachea caused by tracheal stenosis, congenital disorders, and prolonged endotracheal intubation is one of the most difficult procedures in otolaryngology surgery. The main reasons of the failure of tracheal defect reconstruction were strongly related to airway stenosis, airway collapse, and mucus impaction. For more effective trachea reconstruction, artificial trachea transplantation made of polymer matrices has been clinically used. In this study, tracheal reconstruction using polycaprolactone (PCL) asymmetrically porous tube combined with 3D printed PCL scaffold was carried out using a rabbit model. Before the animal study, the mechanical properties of rabbit trachea, PCL tube and/or 3D printed PCL tube were analyzed. From the animal study, we evaluated and compared the endoscopic, radiologic, histologic characterizations, and survival outcomes of the tracheal implant composed of PCL tube and/or 3D printed PCL tube. |
| 저자 |
이진호1, 오세행2, 박수아3, 권성근4, 김태호1, 이소리1
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| 소속 |
1한남대, 2단국대 나노바이오의학과, 3한국기계(연), 4서울대 |
| 키워드 |
Polycaprolactone (PCL) asymmetrically porous tube; 3D printed PCL scaffold
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| E-Mail |
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