| 학회 |
한국고분자학회 |
| 학술대회 |
2003년 가을 (10/10 ~ 10/11, 부경대학교) |
| 권호 |
28권 2호, p.274 |
| 발표분야 |
특별 심포지엄 |
| 제목 |
Sustainable Thermo-Resoponsive Drug Release by Nanodiffusion Mechanism |
| 초록 |
The systematic application of ordered nanoporous materials to themoresponsive controlled drug release using the PNIPAm modified nanoporous materials with different pore sizes. The drug release profiles were obtained for PNIPAm-modified and unmodified nanoporous materials. This approach which involves co-assembly of a chemically-active polymer layer within the ordered porosity of a ceramic matrix holds promise for the novel application to drug delivery system or drug containers with high specificity and throuthput. The results were consistent with the positive squeezing mechanism reported in the literature when the temperature is increased, the release rate peaks rapidly, followed by a very slow release process. |
| 저자 |
장우영1, 장정호1, 김경자1, 강길선2
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| 소속 |
1요업(세라믹)기술원 나노소재응용본부, 2전북대 |
| 키워드 |
PNIPAm; drug; release; nanoporous; nano
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| E-Mail |
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