| 초록 |
We report on the preparation and characterization of polyurethane (PU) composite nanofibers by electrospinning. Two different approaches were adopted to obtain the PU composite nanofibers. In the first approach, a homogeneous solution of 10 wt.% PU containing ciprofloxacin HCl (CipHCl) drug was electrospun to obtain PU/Drug composite nanofibers. And in the second approach, the PU with ciprofloxacin HCl drug and ceramic hydroxyapatite (HA) particles were electrospun to obtain the PU/Drug and PU/Drug/HA composite nanofibers. The surface morphology, structure, bonding configuration, optical and thermal properties of the resultant products were characterized by SEM, XRD, FT-IR, DSC, TGA and UV-vis spectroscopy. The antibacterial activity was tested against common food borne pathogenic bacteria, namely, Staphylococcus aureus, Escherichia coli, by MIC method. Our results demonstrate that these composite nanofibers possess superior characteristics which can utilize for variety of applications |
