화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2013년 가을 (10/23 ~ 10/25, 대구 EXCO)
권호 19권 2호, p.1516
발표분야 생물화공
제목 Identification of Tar Compounds and Effect of these Compounds on the Purification Efficiency of Paclitaxel from Plant Cell Cultures of Taxus chinensis
초록 In this study, the tar compounds derived from the plant cell cultures of Taxus chinensis were first identified and quantified via gas chromatography/mass spectrometry (GC/MS) and gas chromatography (GC). 2-Picoline, 2,5-Xylenol, Acenaphthene, 1-Methylnaphthalene and o-Xylene were found as major main tar components  in biomass. These compounds were identified and confirmed by comparing their retention times with those of authentic compounds. Each compound also spiked with pure standard. The contents of 2-Picoline, 2,5-Xylenol, Acenaphthene, 1-Methylnaphthalene, and o-Xylene in biomass were 0.251, 0.159, 0.124, 0.094 wt% and 0.053 wt%, respectively. In liquid-liquid extraction, adsorbent treatment tar was removed 41.6, 89.1%, respectively. After hexane precipitation, all of tars were successfully removed. Acknowledgement: This work was supported by a grant from the National Research Foundation of Korea (NRF) funded by the Korean government (MEST) (No. 2011-0010907).
저자 김건중, 박규연, 김진현
소속 공주대
키워드 paclitaxel; tar compounds; identification
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