| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 가을 (10/06 ~ 10/08, 제주 ICC) |
| 권호 |
39권 2호 |
| 발표분야 |
대학원생 구두발표 (영어발표, 발표15분) |
| 제목 |
Multifaceted thermoresponsive carbon dot: protein sensors, intracellular thermometer and bioimaging. |
| 초록 |
Herein, we report a new strategy to develop a novel fluorescent thermo responsive polymer/ carbon dot composite in terms of strategy that carboxyl terminated poly (N-vinyl caprolactam) (PVCL-COOH) acts as temperature responsive unit and the C dot is the fluorescent unit. The successfully synthesized hydrophilic PVCL-C dot composites were characterized by 1H NMR, DLS and UV-vis spectra. The variation of fluorescence intensity with temperature was studied. With increasing temperature the PVCL chains shrinks which could also embed some parts of C dot thus resulting in decreased fluorescence intensity. PVCL-C dot showed a significant fluorescence turn-on response to positively charged protein above LCST. Furthermore, the biocompatible PVCL-C dot has been demonstrated as thermometer for sensing intracellular temperature of cells and also in bioimaging. Thus, PVCL-C dot with many advantages is expected to be a novel material with full of promise for biomedical applications. |
| 저자 |
카비싸탕가벨루, 박수영
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| 소속 |
경북대 |
| 키워드 |
Thermoresponsive carbon dot |
| E-Mail |
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