| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
37권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Induction of re-endothelialization by endothelial progenitor cell capturing stent |
| 초록 |
The damage of endothelial layer for stent implantation is a critical factor for restenosis and thrombosis. Restoration of damaged endothelium might be well-built way to reduce late stent thrombosis and restenosis. Some reports demonstrated that endothelial progenitor cell (EPC) can differentiate endothelial cell and then enhance re-endothelialization. In this studies, we evaluated protein immobilized stent might recruit EPC and restore damaged endothelium. Polydopamine coating on metal was accomplished for protein immobilization. Protein was immobilized on polydopamine coated sample. The obtained surface was confirmed by FT-IR and contact angle. EPC capturing protein coated stent might accelerate re-endothelialization and consequently reduce late stent thrombosis and restenosis through the ability of capturing EPC. |
| 저자 |
강성남, 정윤기, 최지연, 한동근
|
| 소속 |
한국과학기술(연) |
| 키워드 |
stent; re-endothelialization; EPC; protein
|
| E-Mail |
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