| 학회 | 한국화학공학회 |
| 학술대회 | 2022년 봄 (04/20 ~ 04/23, 제주국제컨벤션센터) |
| 권호 | 28권 1호, p.1253 |
| 발표분야 | [주제 12] 화학공학일반(부문위원회 발표) |
| 제목 | Glycolic Acid Production in Escherichia coli through the Synergy of L-Arabinose and D-Xylose Metabolic Pathways |
| 초록 | Microbial conversion of C5 sugars to target products is earning momentum as alternative substrates to C6 sugars. In this study, Escherichia coli was engineered to utilize different metabolic pathways responsible for the assimilation of D-xylose and L-arabinose towards glycolic acid (GA) formation. Different L-arabinose metabolic pathways for GA production were first assessed and the most efficient was synergized with the Dahms pathway to produce GA from D-xylose and L-arabinose. Overall, this study is the first to screen for appropriate L-arabinose pathway that explores the synergy between L-arabinose pathway and Dahms pathway for GA production. This work was supported by NRF funded by The Ministry of Science and ICT (2021R1F1A1045612), Basic Science Research Program through the Ministry of Education (2020R1A6A1A03038817). Keywords: D-xylose, L-arabinose, Dahms pathway, glycolic acid, metabolic engineering |
| 저자 | Angelo Banares1, Grace Nisola2, 이원근3, 정욱진4 |
| 소속 | 1명지대, 2Department of Energy Science and Technology (DEST), 3Environmental Waste Recycle Institute (EWRI), 4Myongji Univ. |
| 키워드 | 생물화공(Biochemical Engineering) |
| 원문파일 | 초록 보기 |
