화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관)
권호 34권 2호
발표분야 의료용 고분자 부문위원회
제목 Micro/nanofibrous biocomposite electrospunfrom PCL and silk powder for tissue engineering
초록 Silk has the potential for use as a natural material because of the biocompatibility, degradability, and remarkable mechanical properties. However, although the presence of unique properties of silk leads to biocompatibility and mechanical property compared to synthetic polymeric scaffolds, the lack of reliable and reproducible shape controllability is a drawback. To overcome this problem, nanosized silk powder was electrospun with a biodegradable and biocompatible polymer, polycaprolactone. PCL/silk fibrous composites were fabricated with an electrospinning process. A hydrophilicity, mechanical properties, and cellular behavior of the PCL/silk fibrous scaffold were analyzed. In addition, aligned PCL/silk fibrous webs were fabricated using various collector rotation speeds. As the alignment of micro/nanofibers increased, the hydrophilicity, mechanical properties, and cellular behavior. These results show the potential for using PCL/silk fibrous scaffolds as a good natural biomaterial.
저자 이형진, 김근형
소속 조선대
키워드 eletrospinning; silk; nanofiber
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