| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
생체활성 조직유도 고분자(의료용고분자부문위원회) |
| 제목 |
Biopolymers for an efficient non-viral gene delivery carriers |
| 초록 |
Gene therapy has been studied as an efficient tool for controlled regeneration or specific inhibition of tissue growth. In order to magnify the efficacy of gene therapy, development of powerful gene delivery carrier is essential issue as well as design of therapeutic gene. In this study, we developed various polymeric gene carriers for delivering therapeutic gene into specific cell or tissues such as tumor tissue and muscle cells. Physicochemical characterization of polymers was evaluated followed by gene transfection assay in vitro. Finally, we investigated the efficacy of gene carriers for delivering therapeutic gene in vivo |
| 저자 |
김원종1, 남궁란1, 김성완2
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| 소속 |
1포항공과대, 2유타대 |
| 키워드 |
Gene delivery; Biopolymer; Tissue
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| E-Mail |
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