화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2008년 가을 (10/09 ~ 10/10, 일산킨텍스)
권호 33권 2호
발표분야 기능성 고분자
제목 Effect of various Morphology of PLA Scaffold on Cell Culture
초록 Recently, cell-based therapies, regenerative medicine, and tissue engineering have been progressing rapidly. With the injection of single cell suspensions, the injected cells are expected to remain around the damaged host tissues for the maintenance and recovery of native functions. Polylactide (PLA) has been shown to be important serving as tissue engineering scaffolds and drug delivery carriers because of its good mechanical properties, non-toxicity, processibility, and biodegradability. In this study, three types of PLA scaffolds were prepared and mouse-cell was implanted on PLA scaffolds. The structure of PLA scaffold was characterized by SEM, image analyzer and porosimeter. The cytotoxicity and biocompatibility of the scaffold was measured by WST-1 and microscopes. The result showed the correlation of ability of cell culture and morphology of PLA scaffolds.
저자 이경우1, 조계룡2, 조용우3, 박영환1
소속 1한국생산기술(연), 2숭실대, 3한양대
키워드 PLA; scaffold; cell culture
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