| 학회 |
한국화학공학회 |
| 학술대회 |
2020년 가을 (10/14 ~ 10/16, e-컨퍼런스) |
| 권호 |
26권 1호, p.597 |
| 발표분야 |
이동현상 |
| 제목 |
Synthesis of poly(N-vinylcaprolactam)-based microparticles for thermo-responsive drug delivery |
| 초록 |
Recently, numerious polymers have been developed for drug delivery system because of high biocompatibility and tunable thermo-sensitivity. We introduce thermo-sensitive Poly (N-vinyl caprolactam) hydrogel microparticles synthesized via Stop Flow Lithography (SFL) for controlled drug delivery. Microparticles were collapsed above lower critical solution temperature (LCST) which was adjusted by amount of hydrophilic monomer, as PVCL exhibit LCST. Doxorubicin, as a model drug, was released significantly higher at above LCST than below LCST. The PVCL-based particles accomplished selective drug release depending on temperature, illustrating their feasibility of controlled drug delivery. |
| 저자 |
엄지연1, 문주연1, 홍은지2, 김현웅1, 노윤호1, 심민석2, 봉기완1
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| 소속 |
1고려대, 2인천대 |
| 키워드 |
이동현상 |
| E-Mail |
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| 원문파일 |
초록 보기 |
