| 학회 | 한국공업화학회 |
| 학술대회 | 2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 | 20권 1호 |
| 발표분야 | 나노_포스터 |
| 제목 | Dual-Color Emissive Upconversion Nanocapsules for Differential Cancer Bioimaging In Vivo |
| 초록 | Early diagnosis of tumor malignancy is crucial for timely cancer treatment aimed at imparting desired clinical outcomes. The traditional fluorescencebased imaging is unfortunately faced with challenges such as low tissue penetration and background autofluorescence. Upconversion (UC)-based bioimaging can overcome these limitations as their excitation occurs at lower frequencies and the emission at higher frequencies. In this study, multifunctional silica-based nanocapsules were synthesized to encapsulate two distinct triplet−triplet annihilation UC chromophore pairs. Each nanocapsule emits different colors, blue or green, following a red light excitation. These nanocapsules were further conjugated with either antibodies or peptides to selectively target breast or colon cancer cells, respectively. |
| 저자 | 권오석 |
| 소속 | 한국생명공학(연) |
| 키워드 | upconversion; triplet−triplet annihilation; dual-color; nanocapsule; cancer; imaging; diagnosis |
