화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터)
권호 37권 2호
발표분야 의료용 고분자 부문위원회
제목 Superhydrophobic materials with tunable release of nitric oxide for biomaterials and biomedical applications
초록 Superhydrophobic materials possessing static water contact angles greater than 150° have attracted attention due to diverse applications, including water-repellent and biocompatible surfaces, and materials for controlled drug release. Tremendous techniques have been attempted to impart superhydrophobicity, including lithographic patterning, plasma etching, and chemical vapor deposition. Previously we reported a simple strategy to prepare superhydrophobic surfaces by spray-coating a composite solution of fluorinated silica particles and fluoroalkoxysilane monomers. To extend the utility of such sol-gel-derived superhydrophobic materials, we additionally impart nitric oxide (NO) release ability, a potent anticancer, antimicrobial, and anti-thrombogenic agent. The modulated surfaces are characterized in terms of surface wettability, surface topography, physical durability, and NO release kinetics. Finally, antimicrobial activity of NO-releasing superhydrophobic coatings is demonstrated.
저자 신재호1, 윤종해1, Wesley Storm2, 황은지1, 정우영1, Mark H. Schoenfisch2
소속 1광운대, 2Univ. of North Carolina at Chapel Hill
키워드 Superhydrophobic; nitric oxide; biomaterials
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