| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터) |
| 권호 |
35권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Preparation of Polymeric Nanoparticles Bearing Europium (III) From Poly(glycolic acid-aminophenanethroline-aspartic acid)-co-Poly(L-lactic acid) |
| 초록 |
Biodegradable polymeric nanoparticles have been extensively studied as a drug delivery and bio-imaging system for several decades. In this study, we prepared europium (III) coordinated poly(glycolic acid-aminophenanethroline-aspartic acid)-poly(L-lactic acid) copolymer nanoparticles. Lanthanide ion complexes have sharp emission bands and high photoluminescence efficiency. First, we prepared a poly[Glc-Asp(OBzl)]-poly(L-lactic acid) copolymer by ring opening polymerization of cyclo(glycolic acid-benzylaspartic acid) and L-lactide. After deprotection, the copolymer was reacted with aminophenanethroline. Nanoparticles were obtained by an emulsion-solvent evaporation method from the polymer and an europium (III) complex. We expect that these nanoparticles could be used for bio-imaging. |
| 저자 |
이현표, 장지영
|
| 소속 |
서울대 |
| 키워드 |
Lanthanide; Europium (III); bio-imaging
|
| E-Mail |
|
