| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
19권 2호 |
| 발표분야 |
나노_포스터 |
| 제목 |
Aptamer-functionalized 3-carboxylated polypyrrole plates for highly sensitive Platelet-Drived growth factor biosensor |
| 초록 |
Fast responses and highly selectivity to target biomolecules are require for development of biosensors because that kinds of sensors have been used in medical area to detect various disorder factors. We propose the fabrication of aptamer-functionalized 3-carboxylated polypyrrole plates(A_CPP) for used in a FET sensor to detect platelet-derived growth factor(PDGF_BB). A_CPP are produced by electrodeposition and vapor deposition polymerization steps. The amine functionalized PDGF_B binding aptamer(NH2) are attached carboxylated polypyrrole surface, through covalent bonding. The resulting A_CPP based FET sensors have high sensitivity and selectivity as to PDGF_BB at 1.78fM and among interfering biomolecules. Owing to covalent bonding, a longer life time can be expected for PDGF biosensor. |
| 저자 |
장정식, 이준섭, 김우영, 신동훈
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| 소속 |
서울대 |
| 키워드 |
bio sensor; pyrrole; aptamer
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| E-Mail |
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