| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Polyoxate/Silk Fibroin Film for Bioregeneration of Neo-corneal Endothelial Cells |
| 초록 |
We designed transparent, stable silk films, well-degradable with POX as an alternative scaffold for bioengineering cornea. The morphological and structural properties were analyzed. In vitro biological compatibility was studied. FESEM images display the surface roughness and thickness by the various ratio mixtures of POX and SF. POX content affected in transparency of each POX/SF films but it is not significant except only POX film. Even though differences occur according to ratio of POX and SF, they do not show any significant differences on morphology and well-expressed their functional proteins which are regulated functions of CE. Overall, the results suggest that SF offer good environment on growth of CEnCs and POX plays a role to improve physical properties. POX/SF film may be a suitable alternative for high quality corneal tissue expansion and transplantation. This research was supported by NRF-2012M3A9C6050204 and BK21 PLUS. |
| 저자 |
김은영1, 강길선1, 심보라1, 주천기2, 이동원1
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| 소속 |
1전북대, 2가톨릭대 |
| 키워드 |
Polyoxalte; silk fibroin; corneal endothelial cells
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| E-Mail |
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