화학공학소재연구정보센터
학회 한국재료학회
학술대회 2019년 가을 (10/30 ~ 11/01, 삼척 쏠비치 호텔&리조트)
권호 25권 2호
발표분야 B. 나노화학/바이오 재료 분과
제목 Development of Mg-1.1Mn-1.5Zn/10HA biocomposite using powder metallurgy for bone implant applications
초록 The present paper focusses on the development of magnesium based metal matrix biocomposites using powder metallurgy method for bone implant applications. The effect of surface coatings on the corrosion behavior of the composite was also investigated. Mg-1.5Zn-1.1Mn alloy and Mg-1.5Zn-1.1Mn-10HA composite were mechanically alloyed using ball milling and then sintered at different temperatures (300-450oC) using spark plasma sintering. The surface morphology, chemical composition, phase, mechanical properties and in vitro degradation and biocompatibility studies of composite and coatings were carried out and compared with Mg alloy. SPS of Mg alloyed powders resulted in the lamellar structure of Mg. SEM and XRD data showed that hydroxyapatite (HA) was incorporated and uniformly distributed on Mg alloy matrix after sintering. The compact sintered at 450oC is found to be denser (95%) than other sintered samples. In-vitro degradation tests revealed that Mg-1.5Zn-1.1Mn-10HA composite exhibits lower pH change and hydrogen evolution after immersion in hanks solution for 24h. The composite showed biocompatibility in response of MC3T3-E1 pre-osteoblast cells.
저자 Preeti Makkar1, Byong-Taek Lee2, Soon-jik hoog3
소속 1Institute of Tissue Regeneration, 2College of Medicine, 3Soonchunhyang Univ.
키워드 Magnesium alloy; Mg-1.5Zn-1.1Mn-10HA; Spark plasma sintering; Powder metallurgy; Bone
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