| 학회 |
한국재료학회 |
| 학술대회 |
2013년 봄 (05/23 ~ 05/24, 여수 엠블호텔(THE MVL)) |
| 권호 |
19권 1호 |
| 발표분야 |
D. 바이오재료(Biomaterials) |
| 제목 |
Osteoconductive composites consisting of PEEK and CaO-SiO2 microspheres |
| 초록 |
The osteoconduction is generated from formation of hydroxyapatite (HAp) similar to bone mineral after implantation in bony defects. The HAp formation on the surface of calcium silicate glasses is triggered by dissolution of calcium ions and formation of silanol groups on their surfaces. Sol-gel processing of calcium silicate gives advantage, such as wide compositional regions for HAp formation, and potential on organic modification that allows development of inorganic fillers for composites. The osteoconductive particles in the CaO-SiO2 binary system with the controlled morphology were synthesized through a sol-gel processing. The CaO-SiO2 microsphere showed the potential as filler because they showed HAp formation on their surfaces within 1 day in a simulated body fluid (SBF) which has ion concentrations nearly equal to those in human blood plasma. On the application of the CaO-SiO2 microsphere, osteoconductive composites were fabricated from CaO-SiO2 microsphere and of poly(etheretherketone) (PEEK). In vitro evaluation of HAp formation, the composites formed HAp on their surfaces within 7 days. The periods of HAp deposition on the composites was decreased with increasing the microsphere contents. The mechanical properties of the composites were comparable with that of human cortical bone even after soaking in SBF for 7 days. Consequently, the composites are useful as an artificial bone graft. |
| 저자 |
Ill Yong Kim, Chikara Ohtsuki
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| 소속 |
Nagoya Univ. |
| 키워드 |
CaO-SiO2 system; Sol-gel Processing; Morphology; Composite; Hydroxyapatite
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| E-Mail |
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