| 학회 |
한국화학공학회 |
| 학술대회 |
2016년 가을 (10/19 ~ 10/21, 대전컨벤션센터) |
| 권호 |
22권 2호, p.1824 |
| 발표분야 |
생물화공 |
| 제목 |
SERS-based biosensor for bacterial detection using aptamer-functionalized Raman probe |
| 초록 |
A surface-enhanced Raman scattering (SERS) has been used as a biosensor due to the sensitive and rapid detection of a trace amount of pathogens. The selectivity is also important factor of biosensor for the detection of pathogenic bacteria because they form heterogeneous population in natural environments. Thus it is necessary to fabricate a target-specific substrate in SERS-based biosensor. Herein, the SERS-based biosensor using aptamer-modified Ag@Au core-shell nanoparticles has been developed for the rapid detection of Salmonella typhimurium with high selectivity. The high selectivity and sensitivity was achieved by the modification of target-specific sequenced aptamer and the enhancement of weak Raman scattering due to Ag@Au core-shell nanoparticle. It was possible to quantify S. typhimurium by the correlation between SERS intensity and concentration of S. typhimurium. |
| 저자 |
곽철환1, A.T. Ezhil Vilian2, 유태경3, 한영규2, 허윤석1
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| 소속 |
1인하대, 2동국대, 3경희대 |
| 키워드 |
바이오에너지/환경생물공학 |
| E-Mail |
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| 원문파일 |
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