화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2011년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터)
권호 15권 1호
발표분야 정밀화학
제목 Synthesis and In Vitro Efficacy of tumor targetd Transferrin Poly(ethylene glycol) Paclitaxel Conjugates
초록 The Transferrine-Poly(ethylene glycol)-Paclitaxel (TFPXPEG) was synthesized by reaction of PEG-Paclitaxel (PXPEG) copolymer and Transferrine (TF). TFPXPEG was prepared by chemical reaction PXPEG and TF for Targeted drug delivery system. The structure was investigated by Fourier transform infrared (FT-IR), and ¹H Nuclear magnetic resonance (¹H-NMR), Particle formation was confirmed to become by Transmission electron microscopy (TEM), Electrophoretic LS spectrophotometer (ELS).
저자 박준규, 손동희, 남정표, 김원석, 최창용, 장미경, 나재운
소속 순천대
키워드 Paclitaxel; PEG; Transferrin; cancer therapy
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