| 학회 | 한국화학공학회 |
| 학술대회 | 2006년 가을 (10/27 ~ 10/28, 고려대학교) |
| 권호 | 12권 2호, p.1752 |
| 발표분야 | 생물화공 |
| 제목 | Nanobiochip for ultrasensitive detection of Prostate Cancer based on electrical detection using Scanning Tunneling Microscope |
| 초록 | Prostate Specific Antigen (PSA) is a marker for prostate cancer and it has been identified as a potential marker for breast cancer in women. For the early diagnosis of the prostate cancer and the breast cancer, an ultrasensitive detection system for PSA is being required. In this study, novel ultrasensitive PSA detection method by Scanning Tunneling Microscopy (STM) using gold (Au) nanoparticle-antibody conjugate was developed. As a result, the frequency of current peaks was generated in accordance with the surface density of the dispersed Au nanoparticle on the surface, which was represented as periodogram with its logarithmic regression curve. And, the change of the power spectrum was observed in accordance with the concentration of PSA molecule. Acknowledgements: This work was supported by the Core Environmental Technology Development Project for Next Generation funded by the Ministry of Environment of Korea and by the Nano/Bio science & Technology Program (M10536090001-05N3609- 00110) of the Ministry of Science and Technology (MOST), and by the Brain Korea 21 Project of the Ministry of Education and Human Resources Development |
| 저자 | 장용학, 강다연, 김현희, 오병근, 최정우 |
| 소속 | 서강대 |
| 키워드 | Prostate specific antigen; Gold nanoparticle-antibody conjugate; Electrical detection; Scanning Tunneling Microscopy |
| VOD | VOD 보기 |
| 원문파일 | 초록 보기 |
