| 학회 |
한국공업화학회 |
| 학술대회 |
2011년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터) |
| 권호 |
15권 1호 |
| 발표분야 |
정밀화학 |
| 제목 |
Antioxidant and Depigmenting Activities of Hydroxycinnamoyl-Amino Acidyl-Hydroxamic Acid Derivatives |
| 초록 |
Antioxidant and depigmenting agents have been an important subject of study for the pharmaceutical and the cosmetic industries. Hydroxamic acid is a metal chelator, potentially having tyrosinase inhibitory activity and free radical scavenging activity. Hydroxycinnamic acids (HCA) are well-known phenolic antioxidants existed universally in plants, and showed synergistically enhanced antioxidant activity when conjugated with amino acids. Expecting a synergistic effect, we synthesized a conjugated form of hydroxycinnamic acids and amino acidyl-hydroxamic acid (HCA-AA-NHOH) and confirmed its antioxidant activity and depigmenting activity by various bioassay systems. |
| 저자 |
곽선영1, 공새롬1, 양진경1, 김영부2, 유영애2, 이윤식1
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| 소속 |
1서울대, 2아이피어리스 |
| 키워드 |
Hydroxycinnamic acids; Hydroxamic acid; Amino acid; Antioxidant; Depigmenting Agent
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| E-Mail |
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