화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관)
권호 34권 2호
발표분야 고분자 합성
제목 Self assembly behavior of bioconjugationbetween Nickel complexed nitrilotriacetic acid-polystyrene(NTA-PS) and Histidine tagged green fluorescent protein(GFP)
초록 Polymer-protein bioconjugation has been widely employed in the field of biotechnology and nanotechnology. In this report, we investigate the self-assembly behavior via specific interaction between histidine tagged green fluorescent protein(GFP) and nickel complexed nitrilotriacetic acid-polystyrene(NTA-PS). The self-assembly behavior of the polymer-protein hybrid forms different morphology before and after nickel complexation in DMF/H2O solvent system using different polymer concentration. We synthesized NTA end functionalized polystyrene using Atom Transfer Radical Polymerization. The structures of polymer-protein bioconjugates are confirmed by transmission electron microscopy (TEM) image.
저자 한호석, Nagasundarapandian Soundrarajan, 이선구, 백현종
소속 부산대
키워드 self-assembly behavior; bioconjugation
E-Mail