| 초록 |
Liposomes have been investigated as carriers for cosmetics materials, drugs and contrast agents.We prepared various size liposomes using shirasu porous glass (SPG) emulsification for cosmetics, bio-imaging and cancer chemotheraphy. Liposomes were prepared by the thin film cast-hydration method and were permeated through SPG membrane with decreasing pore diameters of 10, 5, 2, 1, 0.7, 0.5 and 0.2 ㎛. Structures and sizes of liposomes were confirmed by optical microscopy, cryo-TEM and DLS. The time it took liposomes to pass through the SPG membrane was measured at varying pressure, and liposome size was measured with SPG membrane pass number to confirm correlation of SPG membrane and lipid layer of liposomes. |
