| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 봄 (04/10 ~ 04/11, 컨벤션 뷰로(대전)) |
| 권호 |
33권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Chitosan-Lipoic acid nanoparticles for the Vitamin encapsulation |
| 초록 |
The objective of this study is to obtain the anti-oxidant nanoparticles based on biocompatible polymers. It was chosen to conjugate with chitosan as the biodegradable polymer and Lipoic acid(LA) as the hydrophobic anti-oxidant. LA helps in the regeneration of exogenous and endogenous anti-oxidants vitamin as well as glutathione and hence acts as antioxidant indirectly. Chitosan was prepared from chitin which was deacetylated under alkali solution for the various reaction time. Lipoic acid-Chitosan complex was confirmed by FTIR and 1H-NMR. The shapes and sizes of the nanoparticles were investigated with DLS, TEM and SEM. Vitamin as bioactive ingredient incorporated into the micelle. The loading efficiency of vitamin was investigated by HPLC. |
| 저자 |
박은주, 김영진
|
| 소속 |
충남대 |
| 키워드 |
chitosan; lipoic acid; bioactive ingredient; anti-oxidant
|
| E-Mail |
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