| 초록 |
Cyclodextrins are a family of cyclic linked oligosaccharides consisting seven glucose units. They can enhance the solubility and chemical stability and increase the bioavailability. L-Ascorbic acid (AA) is one of the interesting and well known acids in nature which can be used for cosmetic, pharmaceutical, and food industry due to its bioactivity and anti-oxidation. But AA can easily convert into a diketo group, L-dehydroascorbic acid. This study aimed to prepare the novel cosmetic, health food supplement material including β-cyclodextrion (β-CD). The primary hydroxyl groups on β-CD was selectively oxidized to carboxy-β-CD (C-β-CD) using TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl radical). C-β-CD-AA was synthesized as C-β-CD and ascorbic acid with EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide). The synthesized C-β-CD-AA was characterized by FT-IR, 1H-NMR, 13C-NMR spectroscopies. |
