| 초록 |
Ionic liquids (ILs) have characteristic properties such as negligible volatility and nonflammability over a wide temperature range. With these favorable properties, ILs has gained considerable attention as highly promising “green” replacements for conventional hazardous solvents. For lipase-catalyzed kinetic resolution of 1-phenylethanol, highly enhanced selectivity, operational stability, and thermal stability were obtained in some ionic liquids, compared with conventional organic solvents. For the efficient extractive separation of (R)-phenylethyl acetate, its product, ionic liquids/supercritical CO2 system was investigated. Selective extraction to supercritical CO2 provides a new approach for the separation of enantiomers. The enhanced selectivities were observed and the best operating condition for the enantioselective extraction of 1-phenyethyl acetate into CO2 phase in [Edmim][Tf2N] was found at 40°C and 180bar. Under that condition, high enantiomeric excess and conversion were also obtained. At the operating condition, higher selectivity was also obtained when the system scaled-up. |
