| 학회 | 한국공업화학회 |
| 학술대회 | 2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 | 23권 2호 |
| 발표분야 | 포스터_생체재료 |
| 제목 | Dual therapy to treat tumor with magnetic nanoparticles |
| 초록 | Magnetic nanoparticles are used in various fields as biomaterials. Especially, it has great potential as a drug for treating cancer. However, low drug accumulation at the cancer site is a limitation of magnetic nanoparticles as an anticancer drug. In order to get over this limitation of magnetic nanoparticles, we attached materials containing polysaccharide conjugated photosensitizers (MPCP). Polysaccharides give magnetic nanoparticles the ability to target cancer, and photosensitizers allow photodynamic therapy (PDT) to increase anticancer effects. Also, magnetic field gives the magnetic nanoparticles a temperature of up to 43 degrees, allowing for magnetic thermal therapy (MHT). We detected cancer in mouse via MRI (magnetic resonance imaging). In addition, MHT and PDT dual therapy of MPCP proved to increase therapeutic effect in tumor. MPCP expects to take the technology of cancer treatment with nanoparticles to the next level. |
| 저자 | 이태범, 김경섭, 나건 |
| 소속 | 가톨릭대 |
| 키워드 | Magnetic nanoparticles; Photodynamic therapy; Magnetic thermal therapy |
