화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2010년 봄 (05/13 ~ 05/14, BEXCO(부산))
권호 14권 1호
발표분야 나노
제목 Antibiotics Loaded Core-Shell Type Nanofibrous Scaffolds using Coaxial Electrospinning
초록 Antibiotics-loaded core-shell type nanofibrous scaffolds were prepared using coaxial electrospinning. Poly(ε-caprolactone) (PCL) and chitosan with Levofloxacin was used as shell and core respectively, so the antibiotics Levofloxacin electrospinning would be useful for medical applications to treat acute rhinitis. PCL was used to control the release of Levofloxacin with time. The total fiber diameter was about 200 nm while the core diameter was about 100 nm. Since the PCL shell allowed the controlled release of Levofloxacin without an initial burst, the antibiotics-loaded core-shell type nanofibrous scaffolds show promise for treatment of wounds cause by acute rhinitis.
저자 박홍관1, 김중현1, 황태원1, 박태준1, 고원건1, 정인우2
소속 1연세대, 2경북대
키워드 Coaxial electrospinning; nanofiber; core-shell type; antibiotics; sustained release
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