| 초록 |
Poly(ethylene glycol) (PEG) has attracted much attention with its water solubility, biocompatibility, and antifouling effect. However, the lack of functional group within PEG requires modification for further applications. The catechol group, a key element of adhesive property of mussel renders a versatile method to modification of material surfaces. In this study, we polymerized acetonide-protected catechol functionalized glycerol monomer (CAG) using PEG as macroinitiator via anionic ring opening polymerization. A series of catechol functionalized PEG with various molecular weights and catechol contents were synthesized in a controlled manner. The catechol moieties enhance the binding ability of triblock copolymers on the substrate while PEG can inhibit the unspecific binding of biomolecules. We anticipate that this catechol functionalized triblock copolymers will be used in various applications as an antifouling polymer in biomedical fields. |
