| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
| 권호 |
35권 2호 |
| 발표분야 |
고분자 구조 및 물성 |
| 제목 |
Phase transition and microstructure of PLA-PEG block copolymer aqueous solutions as studied by small angle X-ray scattering |
| 초록 |
Polyesters including poly(lactic acid) (PLA), poly(glycolic acid) (PGA), poly(lactic-co-glycolic acid) (PLGA) that have extensive clinical use as FDA-approved materials for resorbable sutures, pins, screws, and staples. PLA has been combined with a hydrophic poly(ethylene glycol) segment to produce an amphiphilic copolymer structure. PLA-PEG diblock copolymers will self-assemble spontaneously in water into a spherical micelle of a few hundred molecules which has a core of densely packed hydrophobic PLA block and a dense PEG brush shell which radiates from the core. And they occur sol-gel transition by various concentration and temperature. However, the variation of microstructure during the phase transition has not been reported. In our work, the aqueous solutions of the synthesized block copolymers with different concentrations were prepared and their sol-gel transitions with the detailed microstructures accompanying the transition were examined by the small angle X-ray scattering. |
| 저자 |
Ngo Le Lam, 태선규, 전혜진, 송현훈
|
| 소속 |
한남대 |
| 키워드 |
PLA-PEG block copolymer; SAXS; block copolymer
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| E-Mail |
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